Clinical Significance of Rab27a as a Urinary Biomarker in Patients With Bladder Cancer
نویسندگان
چکیده
Purpose: The aims of this study were to investigate the clinical value Rab27a as a urinary biomarker, and its efficiency in prediction bladder cancer grade.Materials Methods: expression urine samples patients with cancer, cell line (T-24), tissue was estimated via quantitative reverse transcription polymerase chain reaction (qRT-PCR). level investigated according sex, age, histological grade qRT-PCR Western blotting.Results: also expressed at high levels compared lines tissues from patients. In addition, varied significantly tumor (p<0.001). male elderly patients, however, there not statistically significant.Conclusions: Our results indicated that is valuable diagnostic biomarker for cancer. it may serve predictive factor determining grade.
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ژورنال
عنوان ژورنال: Daehan binyogi jong-yang haksulji
سال: 2022
ISSN: ['2234-4977']
DOI: https://doi.org/10.22465/kjuo.2022.20.1.52